GI Therapies’ technology relates to the use of transcutaneous abdominal gastrointestinal stimulation (TAGS) to deliver interferential electrical stimulation to the abdomen. The first indication for the product (Rhythm IC) is to treat chronic constipation. Clinical trials over the past 10 years using non invasive electrical stimulation applied to the abdomen have shown significant clinical benefit in many patients.
Rhythm.IC is a dedicated non-invasive electrical stimulation device and electrode positioning garment specifically designed for the treatment of chronic constipation. Rhythm.IC incorporates an electrical stimulation unit and the patented neXus® electrode positioning cable and garment.
The product is simple to use, taking only a few minutes to position on the lower abdomen after which the user is free to walk around or undertake daily tasks while the treatment is in session (30-60 minutes/day for 1-3 months). Rhythm.IC applies a comfortable level of electrical stimulation to a patient in their home environment.
After 1-3 months of using Rhythm.IC many patients show a clinically significant improvement in bowel function and quality of life measures. For some patients, the treatment has the prospect of being able to eliminate or significantly reduce their long-term dependence on laxatives or drugs, well after the treatment has stopped.
While the initial clinical trials were undertaken in children, the technology has been shown to be equally effective in adults.
A clinical trial in adults was completed in 2017 and the results presented at the annual Digestive Diseases Week (DDW) conference in the US in June 2018. In summary, a number of clinically and statistically significant improvements were observed including a reduction in abdominal pain, an increase in bowel frequency as well as a number of other symptoms including quality of life measures associated with chronic constipation.
The technology and product design is subject to patent applications either granted or pending in all major markets.